Centro ricerche Dispnea e Ipertensione Polmonare

DIRETTORE

Prof. Sergio Caravita

ÉQUIPE

ATTIVITÀ DI RICERCA

  • Manifestazioni emodinamiche e cardiorespiratorie delle patologie.
  • Emodinamica invasiva, ecocardiografia avanzata, test da sforzo cardiopolmonare.
  • Meccanismi fisiopatologici della dispnea.
  • Ipossia.
  • Trials clinici (ipertensione polmonare / HFpEF).

MALATTIE OGGETTO DI RICERCA

RISULTATI DI PARTICOLARE IMPORTANZA RAGGIUNTI 

Pubblicazioni ultimi 5 anni

  1. Caravita S, Baratto C, Filippo A, Soranna D, Dewachter C, Zambon A, Perego GB, Muraru D, Senni M, Badano LP, Parati G, Vachiéry JL, Fudim M. Shedding light on latent pulmonary vascular disease in heart failure with preserved ejection fraction. JACC Heart Fail 2023, accepted for publication
  2. Baratto C, Faini A, Gallone GP, Dewachter C, Perego GB, Bondue A, Muraru D, Senni M, Badano LP, Parati G, Vachiéry JL, Caravita S. Pulmonary Artery Wedge Pressure and Left Ventricular End-Diastolic pressure during exercise in patients with dyspnea. ERJ Open Res 2023, doi: 10.1183/23120541.00750-2022
  3. Baratto C, Caravita S, Corbetta G, Soranna D, Zambon A, Dewachter C, Gavazzoni M, Heilbron F, Tomaselli M, Radu N, Perelli FP, Perego GB, Vachiéry JL, Parati G, Badano LP. Impact of severe secondary tricuspid regurgitation on rest and exercise hemodynamics of patients with heart failure and a preserved left ventricular ejection fraction. Front Cardiovasc Med. 2023 Mar 1;10:1061118. doi: 10.3389/fcvm.2023.1061118.
  4. Sisinni A, Taramasso M, Praz F, Metra M, Agricola E, Margonato A, Fam N, Estevez-Loureiro R, Latib A, Messika-Zeitoun D, Conradi L, von Bardeleben RS, Sorajja P, Hahn RT, Caravita S, Maisano F, Adamo M, Godino C. Concomitant Transcatheter Edge-to-Edge Treatment of Secondary Tricuspid and Mitral Regurgitation: An Expert Opinion. JACC Cardiovasc Interv. 2023 Jan 23;16(2):127-139. doi: 10.1016/j.jcin.2022.11.022. PMID: 36697147.
  5. Muraru D, Baldea SM, Genovese D, Tomaselli M, Heilbron F, Gavazzoni M, Radu N, Caravita S, Baratto C, Perelli F, Curti E, Parati G, Badano LP. Association of outcome with left ventricular volumes and ejection fraction measured with two- and three-dimensional echocardiography in patients referred for routine, clinically indicated studies. Front Cardiovasc Med. 2022 Dec 22;9:1065131. doi: 10.3389/fcvm.2022.1065131. PMID: 36620642; PMCID: PMC9815115.
  6. Baratto C, Caravita S, Soranna D, Dewachter C, Bondue A, Zambon A, Badano LP, Parati G, Vachiéry JL. An updated meta-analysis of hemodynamics markers of prognosis in patients with pulmonary hypertension due to left heart disease. Pulm Circ. 2022 Oct 1;12(4):e12145. doi: 10.1002/pul2.12145. PMID: 36568693; PMCID: PMC9768568.
  7. Gavazzoni M, Heilbron F, Badano LP, Radu N, Cascella A, Tomaselli M, Perelli F, Caravita S, Baratto C, Parati G, Muraru D. The atrial secondary tricuspid regurgitation is associated to more favorable outcome than the ventricular phenotype. Front Cardiovasc Med. 2022 Nov 29;9:1022755. doi: 10.3389/fcvm.2022.1022755. PMID: 36523369; PMCID: PMC9744784.
  8. Caravita S, Baratto C. Understanding mechanisms of Fontan failure: exercise haemodynamics to unmask diastolic dysfunction, again! Eur J Heart Fail. 2023 Jan;25(1):26-29. doi: 10.1002/ejhf.2756. Epub 2023 Jan 4. PMID: 36519686.
  9. Caravita S, Faini A, Vignati C, Pelucchi S, Salvioni E, Cattadori G, Baratto C, Torlasco C, Contini M, Villani A, Malfatto G, Perger E, Lombardi C, Piperno A, Agostoni P, Parati G. Intravenous iron therapy improves the hypercapnic ventilatory response and sleep disordered breathing in chronic heart failure. Eur J Heart Fail. 2022 Jul 22. doi: 10.1002/ejhf.2628. PMID: 35867685.
  10. Baratto C, Dewachter C, Caravita S, Zambon A, Bondue A, Parati G, Vachiéry JL. Impact of COVID-19 lockdown on exercise capacity in PAH patients. Pulm Circ. 2022 Jul 1;12(3):e12089. doi: 10.1002/pul2.12089. eCollection 2022 Jul.
  11. Caravita S, Picariello C, Garascia A, Misuraca L, De Tommasi E, Imbalzano E, Enea I, Roncon L, Vatrano M, on behalf of the Area Malattie del Circolo Polmonare ANMCO. Pulmonary Hypertension, pre- or post-capillary? The role of the provocative tests in the cath lab. G Ital Cardiol (Rome). 2022 Jul;23(7):533-541. doi: 10.1714/3831.38171
  12. Baratto C, Caravita S, Soranna D, Dewachter C, Bondue A, Zambon A, Badano LP, Parati G, Vachiéry JL. Exercise haemodynamics in heart failure with preserved ejection fraction: a systematic review and meta-analysis. ESC Heart Fail. 2022 Jun 24. doi: 10.1002/ehf2.13979. Epub ahead of print. PMID: 35748109.
  13. Tomaselli M, Badano LP, Menè R, Gavazzoni M, Heilbron F, Radu N, Caravita S, Baratto C, Oliverio G, Florescu DR, Parati G, Muraru D. Impact of correcting the 2D PISA method on the quantification of functional tricuspid regurgitation severity. Eur Heart J Cardiovasc Imaging. 2022 Jun 23:jeac104. doi: 10.1093/ehjci/jeac104. Epub ahead of print. PMID: 35734964.
  14. Vicenzi M, Caravita S, Rota I, Casella R, Deboeck G, Beretta L, Lombi A, Vachiery JL. The added value of right ventricular function normalized for afterload to improve risk stratification of patients with pulmonary arterial hypertension. Plos One 2022, accepted for publication
  15. Naeije R, Caravita S. CPET for Long COVID-19. JACC Heart Fail. 2022 Mar;10(3):214-215. doi: 10.1016/j.jchf.2022.01.008. PMID: 35241250; PMCID: PMC8884263.
  16. Florescu DR, Muraru D, Volpato V, Gavazzoni M, Caravita S, Tomaselli M, Ciampi P, Florescu C, Bălșeanu TA, Parati G, Badano LP. Atrial Functional Tricuspid Regurgitation as a Distinct Pathophysiological and Clinical Entity: No Idiopathic Tricuspid Regurgitation Anymore. J Clin Med. 2022 Jan 13;11(2):382. doi: 10.3390/jcm11020382. PMID: 35054074; PMCID: PMC8781398.
  17. Florescu DR, Muraru D, Florescu C, Volpato V, Caravita S, Perger E, Bălșeanu TA, Parati G, Badano LP. Right heart chambers geometry and function in patients with the atrial and the ventricular phenotypes of functional tricuspid regurgitation. Eur Heart J Cardiovasc Imaging. 2021 Nov 8:jeab211. doi: 10.1093/ehjci/jeab211. Epub ahead of print. PMID: 34747460.
  18. Caravita S, Figliozzi S, Florescu DR, Volpato V, Oliverio G, Tomaselli M, Torlasco C, Muscogiuri G, Cernigliaro F, Parati G, Badano L, Muraru D. Recent advances in multimodality imaging of the tricuspid valve. Expert Rev Med Devices. 2021 Nov;18(11):1069-1081. doi: 10.1080/17434440.2021.1990753. Epub 2021 Oct 27. PMID: 34617481.
  19. Lang M, Paéz V, Maj G, Silva-Urra J, Labarca-Valenzuela C, Caravita S, Faini A, Cantuarias J, Perez O, Bilo G, Parati G. Blood Pressure Response in Miners Exposed to Chronic Intermittent Hypoxia in Chile. Front Cardiovasc Med. 2021 Aug 12;8:701961. doi: 10.3389/fcvm.2021.701961. PMID: 34458335; PMCID: PMC8387657.
  20. Naeije R, Caravita S. Phenotyping long COVID. Eur Respir J. 2021 Aug 26;58(2):2101763. doi: 10.1183/13993003.01763-2021. PMID: 34244323; PMCID: PMC8287735.
  21. Caravita S, Iacovoni A, Senni M. The right side of the circulation in not secondary heart failure with preserved ejection fraction: an elephant in the room? Eur J Heart Fail. 2021 Oct;23(10):1659-1661. doi: 10.1002/ejhf.2294. Epub 2021 Jul 16. PMID: 34231304.
  22. Baratto C, Caravita S, Parati G. Heart failure with preserved ejection fraction and COVID-19: which comes first, the chicken or the egg? Letter regarding the article 'Heart failure with preserved ejection fraction according to the HFA-PEFF score in COVID-19 patients: clinical correlates and echocardiographic findings'. Eur J Heart Fail. 2021 Dec;23(12):2091-2092. doi: 10.1002/ejhf.2273. Epub 2021 Jun 28. PMID: 34145704; PMCID: PMC8426970.
  23. Lang M, Bilo G, Caravita S, Parati G. Presión arterial y altitud: respuestas fisiológicas y manejo clínico [Blood pressure and high altitude: physiological response and clinical management]. Medwave. 2021 May 13;21(4):e8194. Spanish. doi: 10.5867/medwave.2021.04.8194. PMID: 34037579.
  24. Baratto C, Caravita S, Soranna D, Faini A, Dewachter C, Zambon A, Perego GB, Bondue A, Senni M, Badano LP, Parati G, Vachiéry JL. Current Limitations of Invasive Exercise Hemodynamics for the Diagnosis of Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2021 May;14(5):e007555. doi: 10.1161/CIRCHEARTFAILURE.120.007555. Epub 2021 May 6. PMID: 33951935.
  25. Palazzuoli A, Caravita S, Paolillo S, Ghio S, Tocchetti CG, Ruocco G, Correale M, Ambrosio G, Perrone Filardi P, Senni M; Italian Society of Cardiology Heart Failure Study Group. Current gaps in HFpEF trials: Time to reconsider patients' selection and to target phenotypes. Prog Cardiovasc Dis. 2021 Apr 9:S0033-0620(21)00035-9. doi: 10.1016/j.pcad.2021.03.007. Epub ahead of print. PMID: 33839166.
  26. Baratto C, Caravita S, Faini A, Perego GB, Senni M, Badano LP, Parati G. Impact of COVID-19 on exercise pathophysiology. A combined cardiopulmonary and echocardiographic exercise study. J Appl Physiol (1985). 2021 Mar 25. doi: 10.1152/japplphysiol.00710.2020. Epub ahead of print. PMID: 33764166.
  27. Parati G, Caravita S. Personalized exercise prescription as a tool for hypertension management and cardiovascular prevention: evidence and pending issues. Eur J Prev Cardiol. 2021 Mar 24:zwab002. doi: 10.1093/eurjpc/zwab002. Epub ahead of print. PMID: 33758929.
  28. Chomette L, Caravita S, Dewachter C, Abramowicz M, Vachiéry JL, Bondue A. Pulmonary arterial hypertension-associated genetic variants in combined post-capillary and pre-capillary pulmonary hypertension: a case report. Pulm Circ. 2021 Mar 2;11(1):2045894021996571. doi: 10.1177/2045894021996571. PMID: 33738094; PMCID: PMC7934041.
  29. Baratto C, Caravita S, Battista Perego G, Badano LP, Vachiéry JL, Parati G. Systemic Sclerosis and Pulmonary Hypertension: The Great Masquerader. Circ Heart Fail. 2021 Feb;14(2):e007554. doi: 10.1161/CIRCHEARTFAILURE.120.007554. Epub 2021 Jan 28. PMID: 33504158.
  30. Caravita S, Senni M, Parati G. Reply to: 'The hyperdynamic circulatory profile of patients with COVID-19-related acute vascular distress syndrome. Letter regarding the article Haemodynamic characteristics of COVID-19 patients with acute respiratory distress syndrome requiring mechanical ventilation. An invasive assessment using right heart catheterization'. Eur J Heart Fail. 2021 Jan 21. doi: 10.1002/ejhf.2105. Epub ahead of print. PMID: 33480144.
  31. Caravita S, Baratto C, Di Marco F, Calabrese A, Balestrieri G, Russo F, Faini A, Soranna D, Perego GB, Badano LP, Grazioli L, Lorini FL, Parati G, Senni M. Haemodynamic characteristics of COVID-19 patients with acute respiratory distress syndrome requiring mechanical ventilation. An invasive assessment using right heart catheterization. Eur J Heart Fail. 2020 Dec;22(12):2228-2237. doi: 10.1002/ejhf.2058. Epub 2020 Dec 7. PMID: 33200458; PMCID: PMC7753704.
  32. Muraru D, Caravita S, Guta AC, Mihalcea D, Branzi G, Parati G, Badano LP. Functional Tricuspid Regurgitation and Atrial Fibrillation: Which Comes First, the Chicken or the Egg? CASE (Phila). 2020 Jun 6;4(5):458-463. doi: 10.1016/j.case.2020.04.011. PMID: 33117949; PMCID: PMC7581628.
  33. Villani A, Ravaro S, Cerea P, Caravita S, Ciambellotti F, Branzi G, Munforti C, Parati G, Malfatto G. Do the remodeling effects of sacubitril/valsartan treatment depend upon heart failure duration? J Cardiovasc Med (Hagerstown). 2020 Sep;21(9):682-687. doi: 10.2459/JCM.0000000000001000. PMID: 32744827.
  34. Vatrano M, Picariello C, Enea I, Roncon L, Caravita S, De Tommasi E, Imbalzano E, Garascia A, Manes MT, Misuraca L, Urbinati S, Colivicchi F, Gulizia MM, Gabrielli D. Proposta di una lettera di dimissione standardizzata dopo ospedalizzazione per embolia polmonare acuta [Proposal for a standardized discharge letter after hospital stay for acute pulmonary embolism]. G Ital Cardiol (Rome). 2020 Aug;21(8):607-618. Italian. doi: 10.1714/3405.33895. PMID: 32686788.
  35. Picariello C, Caravita S, Vatrano M, Enea I, Roncon L, De Tommasi E, Imbalzano E, Garascia A, Manes MT, Misuraca L, Urbinati S, Colivicchi F, Gulizia MM, Gabrielli D; a nome dell’Area Malattie del Circolo Polmonare ANMCO. Position paper ANMCO: Malattie del circolo polmonare e COVID-19 [ANMCO Position paper: Pulmonary circulation diseases and COVID-19]. G Ital Cardiol (Rome). 2020 Aug;21(8):575-583. Italian. doi: 10.1714/3405.33888. PMID: 32686781.
  36. Badano LP, Caravita S, Rella V, Guida V, Parati G, Muraru D. The Added Value of 3-Dimensional Echocardiography to Understand the Pathophysiology of Functional Tricuspid Regurgitation. JACC Cardiovasc Imaging. 2021 Mar;14(3):683-689. doi: 10.1016/j.jcmg.2020.04.029. Epub 2020 Jul 15. PMID: 32682722.
  37. Quarta G, Gori M, Iorio A, D'Elia E, Moon JC, Iacovoni A, Burocchi S, Schelbert EB, Brambilla P, Sironi S, Caravita S, Parati G, Gavazzi A, Maisel AS, Butler J, Lam CSP, Senni M. Cardiac magnetic resonance in heart failure with preserved ejection fraction: myocyte, interstitium, microvascular, and metabolic abnormalities. Eur J Heart Fail. 2020 Jul;22(7):1065-1075. doi: 10.1002/ejhf.1961. Epub 2020 Aug 7. PMID: 32654354.
  38. Badano LP, Muraru D, Ciambellotti F, Caravita S, Guida V, Tomaselli M, Parati G. Assessment of left ventricular diastolic function by three-dimensional transthoracic echocardiography. Echocardiography. 2020 Nov;37(11):1951-1956. doi: 10.1111/echo.14782. Epub 2020 Jun 28. PMID: 32596833.
  39. Caravita S, Baratto C, Perego GB, Cecchi F, Crotti L, Parati G. Invasive Hemodynamics of Hypertrophic Cardiomyopathy: Exercise Versus Isoproterenol. Circ Heart Fail. 2020 Jun;13(6):e007000. doi: 10.1161/CIRCHEARTFAILURE.120.007000. Epub 2020 Jun 2. PMID: 32482090.
  40. Forton K, Motoji Y, Caravita S, Faoro V, Naeije R. Exercise stress echocardiography of the pulmonary circulation and right ventricular-arterial coupling in healthy adolescents. Eur Heart J Cardiovasc Imaging. 2020 May 7:jeaa085. doi: 10.1093/ehjci/jeaa085. Epub ahead of print. PMID: 32380528.
  41. Paolillo S, Salvioni E, Perrone Filardi P, Bonomi A, Sinagra G, Gentile P, Gargiulo P, Scoccia A, Cosentino N, Gugliandolo P, Badagliacca R, Lagioia R, Correale M, Frigerio M, Perna E, Piepoli M, Re F, Raimondo R, Minà C, Clemenza F, Bussotti M, Limongelli G, Gravino R, Passantino A, Magrì D, Parati G, Caravita S, Scardovi AB, Arcari L, Vignati C, Mapelli M, Cattadori G, Cavaliere C, Corrà U, Agostoni P; MECKI score research group (see Appendix A). Long-term prognostic role of diabetes mellitus and glycemic control in heart failure patients with reduced ejection fraction: Insights from the MECKI Score database. Int J Cardiol. 2020 Oct 15;317:103-110. doi: 10.1016/j.ijcard.2020.04.079. Epub 2020 Apr 29. Erratum in: Int J Cardiol. 2021 Feb 25;: PMID: 32360652.
  42. Roncon L, Picariello C, Vatrano M, Enea I, Caravita S, De Michele L, Vanni S, Casazza F, Zonzin P, Bongarzoni A, D'Agostino C, Azzarito M, Urbinati S, Gulizia MM, Gabrielli D. Modelli diagnostici e terapeutici nel trattamento dell’embolia polmonare acuta: una questione di risorse locali [Diagnostic and therapeutic models for the management of acute pulmonary embolism: an issue of local available resources]. G Ital Cardiol (Rome). 2020 Mar;21(3):179-186. Italian. doi: 10.1714/3306.32766. PMID: 32100730.
  43. Salvioni E, Corrà U, Piepoli M, Rovai S, Correale M, Paolillo S, Pasquali M, Magrì D, Vitale G, Fusini L, Mapelli M, Vignati C, Lagioia R, Raimondo R, Sinagra G, Boggio F, Cangiano L, Gallo G, Magini A, Contini M, Palermo P, Apostolo A, Pezzuto B, Bonomi A, Scardovi AB, Filardi PP, Limongelli G, Metra M, Scrutinio D, Emdin M, Piccioli L, Lombardi C, Cattadori G, Parati G, Caravita S, Re F, Cicoira M, Frigerio M, Clemenza F, Bussotti M, Battaia E, Guazzi M, Bandera F, Badagliacca R, Di Lenarda A, Pacileo G, Passino C, Sciomer S, Ambrosio G, Agostoni P; MECKI score research group. Gender and age normalization and ventilation efficiency during exercise in heart failure with reduced ejection fraction. ESC Heart Fail. 2020 Feb;7(1):371-380. doi: 10.1002/ehf2.12582. Epub 2020 Jan 1. PMID: 31893579; PMCID: PMC7083437.
  44. Abrignani MG, Enea I, Colivicchi F, Roncon L, Aiello A, Becattini C, Bongarzoni A, Caravita S, Dasseni N, De Michele L, Faggiano PM, Mureddu GF, Picariello C, Rao CM, Riccio C, Urbinati S, Vanni S, Vatrano M, Di Lenarda A, Gabrielli D, Gulizia MM. [ANMCO statement: Arterial and venous thromboembolism: what implications for clinical practice?] G Ital Cardiol (Rome). 2019 Nov;20(11):671-684
  45. Malfatto G, Ravaro S, Caravita S, Baratto C, Sorropago A, Giglio A, Tomaselli M, Parati G, Villani A. Improvement of functional capacity in sacubitril-valsartan treated patients assessed by cardiopulmonary exercise test. Acta Cardiol. 2019 Oct 2:1-5
  46. Caravita S, Yerly P, Baratto C, Dewachter C, Faini A, Rimouche A, Branzi G, Perego GB, Bondue A, Parati G, Vachiéry JL. Non-invasive versus invasive pressure/flow relationship of the pulmonary circulation: bias and error. Eur Respir J. 2019 Sep 26. pii: 1900881.
  47. Senni M, Caravita S, Paulus WJ. Do Existing Definitions Identify Subgroup Phenotypes or Reflect the Natural History of Heart Failure With Preserved Ejection Fraction? Circulation. 2019 Jul 30;140(5):366-369
  48. Forton K, Motoji Y, Pezzuto B, Caravita S, Delbaere A, Naeije R, Faoro V. Decreased pulmonary vascular distensibility in adolescents conceived by in vitro fertilization. Hum Reprod. 2019 Sep 29;34(9):1799-1808
  49. Baratto C, Caravita S, Perego GB, Parati G. Stiff left atrial syndrome after low-dose radiotherapy for right breast cancer: The need for invasive hemodynamics at exercise. Catheter Cardiovasc Interv. 2019 Jun 13. doi: 10.1002/ccd.28348
  50. Bilo G, Caravita S, Torlasco C, Parati G. Blood pressure at high altitude: physiology and clinical implications. Kardiol Pol. 2019 Jun 25;77(6):596-603. doi: 10.33963/KP.14832
  51. Lombardi C, Faini A, La Rovere M, Fanfulla F, Mattaliano P, Caravita S, Contini M, Agostoni P, Perrone-Filardi P, Parati G; PROMISES Investigators. Heart failure and sleep related breathing disorders: Data from PROMISES (Progetto Multicentrico Italiano Sonno e Scompenso Cardiaco) study. Int J Cardiol. 2018;271:140-145
  52. Caravita S, Mariani D, Blengino S, Branzi G, Crotti L, Parati G. Pulmonary hypertension due to a stiff left atrium: Speckle tracking equivalents of large V-waves. Echocardiography 2018;35:1464-1466.
  53. Caravita S, Faini A, Carolino D’Araujo S, Dewachter C, Chomette L, Bondue A, Naeije R, Parati G, Vachiéry JL. Clinical phenotypes and outcomes of pulmonary hypertension due to left heart disease: role of the pre-capillary component. Plos One 2018;13(6):e0199164
  54. Caravita S, Faini A, Baratto C, Bilo G, Macarlupu JL, Lang M, Revera M, Lombardi C, Villafuerte FC, Agostoni P, Parati G. Upward shift and steepening of the blood pressure response to exercise in hypertensive subjects at high altitude. J Am Heart Assoc 2018;7(12):pii:e008506
  55. Caravita S, Dewachter C, Soranna D, Carolino D'Araujo S, Khaldi A, Zambon A, Parati G, Bondue A, Vachiéry JL. Haemodynamics to predict outcome in pulmonary hypertension due to left heart disease: a meta-analysis. Eur Respir J. 2018 Feb 8. pii: 1702427. doi: 10.1183/13993003.02427-2017

Riconoscimenti e awards

Il Prof. Caravita è stato membro del comitato di coordinamento dell’area malattie del circolo polmonare dell’Associazione Nazionale Medici Cardiologi Ospedalieri nel biennio 2017-2018, membro del comitato scientifico nel 2019-2021, e medical writer nel biennio 2022-2023.

La pubblicazione “Impact of COVID-19 on exercise pathophysiology. A combined cardiopulmonary and echocardiographic exercise study” ha ottenuto il riconoscimento di “paper of the year 2021” (Journal of Applied Physiology).

Il Prof. Caravita ha ricevuto il Premio “Digital ANMCO 2022” – 53° Congresso Nazionale ANMCO.

Il Prof. Caravita ha ricevuto il Grant SIC-PIAM Pharma 2021, 82° Congresso Nazionale SIC.

Il Dr. Baratto ha ricevuto il Research Grant ESC 2020.

Il Prof. Caravita ha ricevuto il Secondo premio “Vera Srebot” 2018, Fondazione CNR/Regione Toscana per la Ricerca Medica e di Sanità Pubblica.

PRINCIPALI COLLABORAZIONI A NETWORK DI RICERCA NAZIONALI E INTERNAZIONALI

The pulmonary haemodynamics during exercise – research network (PEX-NET) ERS Clinical Research Collaboration.

Clinica dell’Ipertensione Polmonare e dell’Insufficienza cardiaca, Hopital Erasme, Brussels, Belgio (Prof JL Vachiéry).

Duke University, NC, USA (Prof M Fudim).

English version