Dott.ssa Noela Radu

2007 - 2011
Diploma di maturità scientifica (Voto finale 9.7/10) presso il Collegio Nazionale “Fratii Buzesti", Craiova, Romania.

2011 - 2017
Laurea Magistrale in Medicina e Chirurgia (Voto finale 9.53/10) presso l'Università di Medicina e Farmacia “Carol Davila”, Bucarest, Romania. 

2018 - 2023 
Specializzazione in Cardiologia, Ministero della Salute - Istituto di Emergenza per le Malattie Cardiovascolari “Prof. Dr. C.C. Iliescu”, Bucarest, Romania.

2022
Assegnista di ricerca/Fellowship in Ecocardiografia Avanzata presso l'Università degli studi Milano-Bicocca, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milano, Italia.

2023 - 2024
Assistente universitario presso l'Università di Medicina e Farmacia “Carol Davila”, Istituto di Emergenza per le Malattie Cardiovascolari “Prof. Dr. C.C. Iliescu”, Bucarest, Romania.

2024
Specialista di Malattie dell'apparato cardiovascolare (Voto finale 9.74/10), Ministero della Salute, Bucarest, Romania.

• Ecocardiografia di base e avanzata (ecocardiografia speckle-tracking e tridimensionale, ecografia transesofagea, eco stress farmacologico con dobutamina e dipiridamolo, ecocardiografia con mezzo di contrasto, ecodoppler transcranico);
• Imaging cardiovascolare multimodale;
• Imaging cardiovascolare avanzato nelle valvulopatie.

• Imaging ecocardiografico avanzato nelle valvulopatie (insufficienza mitralica e tricuspidalica);
• Ecocardiografia avanzata (Ecocardiografia tridimensionale, speckle-tracking);
• Applicazione dell’intelligenza artificiale nelle valvulopatie;
• Stratificazione del rischio cardiovascolare mediante tecniche ecocardiografiche avanzate.

Partecipazioni a convegni

• Congresso EACVI 2024: “Advanced echocardiography and cluster analysis to identify secondary tricuspid regurgitation phenogroups at different risk” - Relatore -  Vincitore del II premio “Young Investigator Award Basic Science”
• Congresso EACVI 2023: “Mechanical adaptation of the right ventricle to increased volume overload associated with secondary tricuspid regurgitation” - Relatore - Partecipante alla competizione “Young Investigator Award Basic Science”.
  “Right ventricular-pulmonary artery coupling ratio derived from 3D echocardiography-better predictor of outcome in patients with precapillary pulmonary hypertension” - Relatore
• Congresso Nazionale Romeno 2022: “Right ventricular-pulmonary artery coupling ratio derived from 3D echocardiography-better predictor of outcome in patients with precapillary pulmonary hypertension” - Relatore - Vincitore del I premio “Young Investigator Award”.
  “Prognostic power of a new index of right ventricle-pulmonary artery coupling based on right ventricular volumes in patients with secondary tricuspid regurgitation” – Relatore - Vincitore del II premio “Rapid fire abstracts”.

Pubblicazioni

Articoli originali pubblicati su riviste internazionali indicizzate Thomson ISI

1. Benzoni G, Tomaselli M, Radu N, Clement A, Penso M, Springhetti P, Conforme Torres DI, Rinforzi T, Tosi C, Buta A, Kawada Y, Muraru D, Badano LP. Threshold Values of the Vena Contracta Area for Grading Secondary Tricuspid Regurgitation and its Association with Outcomes. J Am Soc Echocardiogr. 2025 Oct 31:S0894-7317(25)00607-8. doi: 10.1016/j.echo.2025.10.015. Epub ahead of print. PMID: 41177341.
2. Buta AS, Badano LP, Penso M, Tomaselli M, Kawada Y, Radu ND, Clement A, Springhetti P, Fisicaro S, Heilbron F, Benzoni G, Pece C, Damiani F, Franciosi F, Popescu BA, Muraru D. Refining tricuspid regurgitation severity assessment with new corrected proximal isovelocity surface area threshold values. Eur Heart J Cardiovasc Imaging. 2025 Oct 6:jeaf288. doi: 10.1093/ehjci/jeaf288. Epub ahead of print. PMID: 41052282.
3. Michele Tomaselli, Marco Penso, Luigi P Badano, Noela Radu, Paolo Springhetti, Alexandra Buta, Giorgia Benzoni, Diana R Hădăreanu, Sergio Caravita, Claudia Baratto, Alexandra Clement, Samantha Fisicaro, Marie-Annick Clavel, Denisa Muraru. Sex-specific differences in right heart remodelling and patient outcomes in secondary tricuspid regurgitation, European Heart Journal – Cardiovascular Imaging, 2025; https://doi.org/10.1093/ehjci/jeaf215
4. Luigi P. Badano, Marco Penso, Michele Tomaselli, Kyu Kim, Alexandra Clement, Noela Radu, Geu-Ru Hong, Diana R. Hădăreanu, Alexandra Buta, Caterina Delcea, Samantha Fisicaro, Gianfranco Parati, Chi Young Shim, Denisa Muraru. Advanced echocardiography and cluster analysis to identify secondary tricuspid regurgitation phenogroups at different risk, Revista Española de Cardiología (English Edition), 2025, ISSN 1885-5857; https://doi.org/10.1016/j.rec.2025.02.004.
5. Michele Tomaselli, Marco Penso, Luigi P. Badano, Alexandra Clement, Noela Radu, Francesca Heilbron, Mara Gavazzoni, Diana R. Hădăreanu, Giorgio Oliverio, Samantha Fisicaro, Paolo Springhetti, Cinzia Pece, Caterina Delcea, Denisa Muraru. Association With Outcomes of Correcting the Proximal Isovelocity Surface Area Method to Quantitate Secondary Tricuspid Regurgitation, Journal of the American Society of Echocardiography, Volume 38, Issue 3, 2025; https://doi.org/10.1016/j.echo.2024.10.015.
6. Alexandra Clement, Denisa Muraru, Samantha Fisicaro, Marco Penso, Michele Tomaselli, Noela Radu, Caterina Delcea, Alexandra S. Buta, Valeria Rella, Radu Sascau, Luigi P. Badano. Utility of the Ratio Between the Size of the Right Atrium and the Right Ventricle at End-Systole to Diagnose Atrial Secondary Tricuspid Regurgitation, Journal of the American Society of Echocardiography, Volume 38, Issue 3, 2025, Pages 212-223, ISSN 0894-7317; https://doi.org/10.1016/j.echo.2024.11.012
7. Alexandra Clement, Michele Tomaselli, Luigi P. Badano, Diana R. Hadareanu, Noela Radu, Marco Penso, Sergio Caravita, Claudia Baratto, Samantha Fisicaro, Caterina Delcea, Alessandra Rota, Radu Sascau, Denisa Muraru. Association With Outcome of the Regurgitant-Volume Adjusted Right Ventricular Ejection Fraction in Secondary Tricuspid Regurgitation, Journal of the American Society of Echocardiography, Volume 38, Issue 6, 2025, Pages 451-464, ISSN 0894-7317;https://doi.org/10.1016/j.echo.2025.01.008
8. Zsuzsanna Ladányi, Bálint Károly Lakatos, Alexandra Clement, Michele Tomaselli, Alexandra Fábián, Noela Radu, Tímea Katalin Turschl, Andrea Ferencz, Béla Merkely, Elena Surkova, Attila Kovács, Denisa Muraru, Luigi P. Badano. Mechanical Adaptation of the Right Ventricle to Secondary Tricuspid Regurgitation and Its Association With Patient Outcomes, Journal of the American Society of Echocardiography, Volume 38, Issue 7, 2025, ISSN 0894-7317; https://doi.org/10.1016/j.echo.2025.02.011
9. Paolo Springhetti, Michele Tomaselli, Leonardo Portolan, Marco Penso, Jessica Pizzini, Denis Leonardi, Alexandra Clement, Luca Ciceri, Noela Radu, Giorgia Benzoni, Roberto Scarsini, Flavio Ribichini, Denisa Muraru, Giovanni Benfari, Luigi P. Badano, Transaortic Flow Rate and RiskStratification in Moderate Aortic Stenosis, Journal of the American Society of Echocardiography, Volume 38, Issue 8, 2025, Pages 643-654, ISSN 0894-7317; https://doi.org/10.1016/j.echo.2025.02.01
10. Michele Tomaselli, Marco Penso, Luigi P. Badano, Alexandra Clement, Noela Radu, Francesca Heilbron, Giorgia Benzoni, Diana R. Hădăreanu, Paolo Springhetti, Oliverio Giorgio, Sergio Caravita, Claudia Baratto, Antonio Sorropago, Samantha Fisicaro, Gianfranco Parati, Denisa Muraru, Right Ventricular Function and Outcomes Stratified by the Effective Regurgitant Orifice Area in Secondary Tricuspid Regurgitation, Canadian Journal of Cardiology,Volume 41, 2025;https://doi.org/10.1016/j.cjca.2025.01.006
11. Michele Tomaselli, Paolo Springhetti, Giovanni Benfari, Marco Penso, Alexandra Clement, Matteo Pilan, Denis Leonardi, Luca Ciceri, Alexandra Buta, Roberto Scarsini, Andreea Calin, Claudia Nitu, Noela Radu, Denisa Muraru, Bogdan A Popescu, Flavio Ribichini, Luigi P Badano, A novel staging system of cardiac damage in aortic stenosis based on multi-chamber myocardial deformation, European Heart Journal - Cardiovascular Imaging, Volume 26, Issue 5, May 2025; https://doi.org/10.1093/ehjci/jeaf035
12. Máté Tolvaj, Attila Kovács, Noela Radu, Andrea Cascella, Denisa Muraru, Bálint Lakatos, Alexandra Fábián, Márton Tokodi, Michele Tomaselli, [...], Luigi P. Badano, Elena Surkova, Significant Disagreement Between Conventional Parameters and 3D Echocardiography-Derived Ejection Fraction in the Detection of Right Ventricular Systolic Dysfunction and Its Association With Outcomes, Journal of the American Society of Echocardiography, Volume 37, 2024; https://doi.org/10.1016/j.echo.2024.04.005
13. Tomaselli M, Radu DN (shared first author), Badano LP, Perelli FP, Heilbron F, Cascella A, Gavazzoni M, Hadareanu DR, Mihaila S, Oliverio G, Penso M, Caravita S, Baratto C, Fisicaro S, Parati G, Muraru D. Right atrial remodeling in patients with secondary tricuspid regurgitation. Journal of the American Society of Echocardiography 2024; vol 37, issue 5: 495-505.e3. ISSN 0894-7317, doi: 10.1016/j.echo.2024.01.003
14. Badea R, Enache R, Predescu LM, Platon P, Catana N, Deleanu D, Iosifescu AG, Radu N, Radu T, Olaru-Lego G, Coman IM, Popescu BA. Left main coronary artery compression in precapillary pulmonary hypertension. Pulm Circ. 2024; 14:e12391; https://doi.org/10.1002/pul2.12391
15. Gavazzoni M, Badano LP, Cascella A, Heilbron F, Tomaselli M, Caravita S, Baratto C, Perelli FP, Radu N, Perger E, Parati G, Muraru D. Clinical value of a novel three-dimensional echocardiography – derived index of right ventricle-pulmonary artery coupling in tricuspid regurgitation. Journal of the American Society of Echocardiography 2023; vol 36, issue 11: 1154-1166.e3. ISSN 0894-7317, doi.org/10.1016/j.echo.2023.06.014.
16. Baratto C, Caravita S, Corbetta G, Soranna D, Zambon A, Dewachter C, Gavazzoni M, Heilbron F, Tomaselli M, Radu N, Perelli F, Perego GB, Vachiery JL, Parati G, Badano LP, Muraru D. Impact of severe secondary tricuspid regurgitation on rest and exercise hemodynamics of patients with heart failure and a preserved left ventricular ejection fraction. Frontiers In – Cardiovascular Medicine 2023; 10: 1061118. ISSN: 2297-055X. doi: 10.3389/fcvm.2023.1061118. Impact factor (2024):  3.6.
17. Muraru D, Mihaila M, Genovese D, Tomaselli M, Heilbron F, Gavazzoni M, Radu N, Caravita S, Baratto C, Perelli F, Curti E, Parati G, Badano LP. Association of outcome with left ventricular volumes and ejection fraction measured with two- and three-dimensional echocardiography in patients referred for routine, clinically indicated studies. Frontiers In – Cardiovascular Medicine 2022; 9: 1065131. ISSN: 2297-055X. doi: 10.3389/fcvm.2022.1065131. Impact factor (2024):  3.6.
18. Gavazzoni M, Heilbron F, Badano LP, Radu N, Cascella A, Tomaselli M, Perelli F, Caravita S, Baratto C, Parati G, Muraru D. The atrial secondary tricuspid regurgitation is associated to more favorable outcome than the ventricular phenotype. Frontiers In – Cardiovascular Medicine 2022; 9: 1022755. ISSN: 2297-055X. doi: 10.3389/fcvm.2022.1022755. Impact factor (2024):  3.6.
19. Muraru D, Gavazzoni M, Heilbron F, Mihalcea DJ, Guta AC, Radu N, Muscogiuri G, Tomaselli M, Sironi S, Parati G, Badano LP. Reference ranges of tricuspid annulus geometry in healthy adults using a dedicated three-dimensional echocardiography software package. Frontiers In – Cardiovascular Medicine 2022; 9: 1011931. ISSN: 2297-055X. doi: 10.3389/fcvm.2022.1011931. Impact factor (2024):  3.6.
20. Tomaselli M, Badano LP, Mene R, Gavazzoni M, Heilbron F, Radu N, Caravita S, Baratto C, Oliverio G, Florescu DR, Parati G, Muraru D. Impact of correcting the 2D PISA method on the quantification of functional tricuspid regurgitation severity. European Heart Journal – Cardiovascular Imaging 2022; vol 23, issue 11: 1459-1470. ISSN: 2047-2404. doi: 10.1093/ehjci/jeac104. Impact factor (2023):  6.3.
21. Radu DN, Dobrovie M, Capsa R, Enache R. Neurofibromatosis 1 – Noonan syndrome associated with pulmonary stenosis and hypertrophic cardiomyopathy. Romanian Journal of Cardiology 2021, vol. 31, no. 4: 903-910.
22. Hernic A, Enache R, Radu DN, Coman IM, Ginghina C. The heroic chamber – an outlook on the right ventricle in Eisenmenger syndrome. Romanian Journal of Cardiology 2021, vol. 31, no. 4: 837-846.
23. Bucsa A, Radu DN, Enache R, Rosca M, Calin A, Predescu L, Popescu BA. Secondary ischemic mitral regurgitation in a young patient - therapeutic approach. Romanian Journal of Cardiology 2019; vol. 29, no. 3: 464-470.
24. Radu DN, Dorobanțu DM, Enache R. Clinical and echocardiographic aspects in fixed subaortic stenosis. Romanian Journal of Cardiology 2018; vol. 28, no. 4: 305-312.

• Membro della Società Europea di Cardiologia (ESC) (10/2018)
• Membro della Società Europea di Imaging Cardiovascolare (EACVI) (10/2018)
• Membro della Società Romena di Cardiologia (10/2018)